Searchable abstracts of presentations at key conferences in endocrinology

ea0031p195 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2013

Replication of genome wide association-validated loci for type 2 diabetes mellitus in the Saudi Arabian population

Al-Daghri Nasser , Alkharfy Khalid , Alokail Majed , Alenad Amal , Al-Attas Omar , Mohammad Abdul Khader , Sabico Shaun , Albagha Omar

Background: Previous genome wide association studies in Caucasian and South Asian populations have identified over 35 loci for type 2 diabetes mellitus (T2DM) risk. However, little is known about the contribution of these loci in T2DM from a Saudi Arabian population. In this study we investigated for the first time, the association of 38 previously identified T2DM risk loci (32 loci from Caucasian and six loci from South Asian populations) in 1166 T2DM patients and 1235 health...